In questa metanalisi sono stati selezionati dalla letteratura 16 studi nei quali è stato utilizzato PRO nel ringiovanimento facciale. Nonostante lalta variabilità dei metodi di preparazione del PRP, delle modalità di somministrazione, la possibile associazione ad altre metodiche e leterogeneità dei criteri di valutazione degli effetti, i risultati sembrano indicare una azione promettente del PRP sulle rughe, qualità della cute e pigmentazioni cui sembrano corrispondere interessanti rimodellamenti istologici. E evidente la necessità di studi randomizzati controllati per ottenere dati sui quali costruire linee guida operative.
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In this meta-analysis, 16 studies were selected from the literature in which PRO was used in facial rejuvenation. Despite the high variability of the PRP preparation methods, the administration methods, the possible association with other methods and the heterogeneity of the effect evaluation criteria, the results seem to indicate a promising action of PRP on wrinkles, quality of skin and pigmentations which seem to correspond to interesting histological remodeling. The need for randomized controlled studies to obtain data on which to build operational guidelines is evident.
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(dott. Miranda Rosario)
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Neiva-Sousa M, Carracha C, Nunes da Silva L, Valejo Coelho P. Does Platelet-Rich Plasma Promote Facial Rejuvenation? Revising the Latest Evidence in a Narrative Review <pubmed.ncbi.nlm.nih.gov/38314356/> . J Cutan Aesthet Surg. 2023 Oct-Dec;16(4):263-269.
Abstract
Facial aging is characterized by progressive macroscopic, histological, and molecular changes. Due to its regenerative and rejuvenating properties, the use of platelet-rich plasma (PRP) as a facial antiaging agent has gained popularity over the last decade. In order to gather and evaluate the latest evidence focusing on the effect of PRP on facial skin rejuvenating, a search through MEDLINE (PubMed) using relevant keywords, inclusion, and exclusion criteria was performed. A total of 539 articles were initially retrieved, and from those, 16 were included in the review. Treatment protocols comprised the use of PRP both in monotherapy and in combination with other substances and by means of direct injection or topical application following skin permeation. The selected studies presented high variability regarding PRP preparation methods, administration protocols, and results assessment. In most studies, PRP seemed to improve to some degree the signs of facial aging, such has wrinkles, skin quality, and pigmentation, accompanied by significant histological and molecular responses. Optimizing treatment protocols should be the next step in assessing the full potential of PRP.
Keywords:
Aging; PRP; face; hyperpigmentation; platelet-rich plasma; rejuvenation; skin; wrinkles.
Image by Freepik
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In this meta-analysis, 16 studies were selected from the literature in which PRO was used in facial rejuvenation. Despite the high variability of the PRP preparation methods, the administration methods, the possible association with other methods and the heterogeneity of the effect evaluation criteria, the results seem to indicate a promising action of PRP on wrinkles, quality of skin and pigmentations which seem to correspond to interesting histological remodeling. The need for randomized controlled studies to obtain data on which to build operational guidelines is evident.
.
(dott. Miranda Rosario)
..
.
Neiva-Sousa M, Carracha C, Nunes da Silva L, Valejo Coelho P. Does Platelet-Rich Plasma Promote Facial Rejuvenation? Revising the Latest Evidence in a Narrative Review <pubmed.ncbi.nlm.nih.gov/38314356/> . J Cutan Aesthet Surg. 2023 Oct-Dec;16(4):263-269.
Abstract
Facial aging is characterized by progressive macroscopic, histological, and molecular changes. Due to its regenerative and rejuvenating properties, the use of platelet-rich plasma (PRP) as a facial antiaging agent has gained popularity over the last decade. In order to gather and evaluate the latest evidence focusing on the effect of PRP on facial skin rejuvenating, a search through MEDLINE (PubMed) using relevant keywords, inclusion, and exclusion criteria was performed. A total of 539 articles were initially retrieved, and from those, 16 were included in the review. Treatment protocols comprised the use of PRP both in monotherapy and in combination with other substances and by means of direct injection or topical application following skin permeation. The selected studies presented high variability regarding PRP preparation methods, administration protocols, and results assessment. In most studies, PRP seemed to improve to some degree the signs of facial aging, such has wrinkles, skin quality, and pigmentation, accompanied by significant histological and molecular responses. Optimizing treatment protocols should be the next step in assessing the full potential of PRP.
Keywords:
Aging; PRP; face; hyperpigmentation; platelet-rich plasma; rejuvenation; skin; wrinkles.
Image by Freepik
